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1.
Int. j. morphol ; 41(5): 1400-1410, oct. 2023. ilus, tab, graf
Article in Spanish | LILACS | ID: biblio-1521011

ABSTRACT

La dactiloscopía o papiloscopía corresponde al estudio científico de las impresiones digitales, palmares y plantares, que tiene por finalidad la identificación infalible o indubitada del individuo. Existen tres niveles para identificar con mayor certeza nivel 1 (tipo o patrón dactilar), el nivel 2 (minucias o puntos característicos) y el nivel 3 (poroscopia y crestoscopia). Por ello, es necesario analizar las características de las impresiones dactilares directas y las huellas dactilares directas con la finalidad de verificar la presencia de puntos y poros característicos para mejorar el proceso de identificación humana. Se analizaron 80 muestras (54 mujeres y 26 hom- bres). A partir de ellos, se capturaron 800 impresiones y 800 huellas dactilares directas con tampón dactilar y polvo black. En huellas con tampón se identificaron 71.25 % y 1.25 % con 14 y 6 Puntos Característicos respectivamente y en grupos de poros el 84 % y 35 % para un grupo de 1 y grupos de 7 y 8 poros respectivamente. Con polvo black solo se identificaron Puntos Característico y no Poros. La cantidad de poros en hombres fue mayor igual a 10 (LR= 2.08) y en mujeres menor igual a 6 (LR= 1.93). Los grupos de poros fueron para hombres menores o iguales a 12 poros (LR= 1.04) y mayores o iguales a grupos de 13 poros (LR=1.28) para mujeres. Se consiguieron identificar grupos de poros con tampón dactilar pero no con polvos químicos lo que podría emplearse para implementar un protocolo para el uso del nivel 3 de identificación.


SUMMARY: Dactyloscopy or papiloscopy corresponds to the scientific study of digital, palmar and plantar impressions, whose purpose is the infallible or indubitable identification of a subject. There are three levels to identify with greater certainty level 1 (type or fingerprint pattern), level 2 (minutiae or characteristic points) and level 3 (poroscopy and crestoscopy). Therefore, it is necessary to analyze the characteristics of direct fingerprints and direct fingerprints in order to verify the presence of characteristic points and pores to improve the human identification process. 80 samples (54 women and 26 men) were analyzed. Of these, 800 impressions and 800 direct fingerprints with fingerprint buffer and black powder were captured. In footprints with buffer, 71.25 % and 1.25 % were identified with 14 and 6 Characteristic Points respectively and in groups of pores 84 % and 35 % for a group of 1 and groups of 7 and 8 pores respectively. With black powder, only Characteristic Points and no Pores were identified. The number of pores in men was greater than 10 (LR= 2.08) and in women less than 6 (LR= 1.93). The groups of pores were less than or equal to 12 pores (LR= 1.04) for men and greater than or equal to groups of 13 pores (LR=1.28) for women. It was possible to identify groups of pores with a fingerprint buffer but not with chemical powders, which could be used to implement a protocol for the use of level 3 identification.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Young Adult , Forensic Anthropology/methods , Dermatoglyphics , Peru , Pilot Projects
2.
Rev. Fac. Med. Hum ; 23(2)abr. 2023.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1514787

ABSTRACT

Introducción: Los adultos mayores son suscepctibles a la malnutrición y el déficit de vitaminas. Objetivo: Determinar la asociación entre el bajo nivel de vitamina B12 y el deterioro cognitivo en adultos mayores del centro médico naval, ubicado en Lima-Perú, en el periodo 2010-2015. Métodos : Se realizó un estudio transversal analítico, a partir de un análisis secundario de la base de datos Texas-Cemena UTMB 2010-2015 del centro de investigación del envejecimiento (CIEN) de la Universidad De San Martín De Porres. Para la cuantificación de la variable de deterioro cognitivo se utilizó el MiniMental test. Para analizar la asociación, se realizó la prueba de chi cuadrado y la regresión de Poisson. Resultados : El 57,6% de los pacientes fueron de sexo masculino y la edad promedio fue de 78 ± 8,4. El 41,2% presentó deterioro cognitivo y el 9,5% de los pacientes presentó déficit de vitamina b12. Los factores independientemente asociados al deterioro cognitivo fueron el antecedente de enfermedad cerebro vascular (RP= 1,38 IC 95% [1,24-1,53]), depresión (RP = 1,88 IC 95% [1,80-1,97]),) y déficit de vitamina B12 (RP = 1,10 ic 95% [1,01-1,20]),). Conclusiones : En el presente estudio se encontró asociación entre un bajo nivel de vitamina B12 y el deterioro cognitivo en adultos mayores.


Introduction: Older adults are susceptible to malnutrition and vitamin deficiency. Objective: To determine the association between the low level of vitamin B12 and cognitive deterioration in older adults from the Naval Medical Center, located in Lima-Peru, in the period 2010-2015. Methods: An analytical cross-sectional study was carried out, based on a secondary analysis of the Texas-Cemena UTMB 2010-2015 database of the center for research on aging (cien) of The University Of San Martín De Porres. To quantify the cognitive impairment variable, the mini mental test was used. To analyze the association, the chi-square test and poisson regression were performed. Results: 57.6% of the patients were male and the mean age was 78 ± 8.4. 41.2% presented cognitive deterioration and 9.5% of the patients presented vitamin B12 deficiency. The factors independently associated with cognitive impairment were a history of cerebrovascular disease (pr= 1.38 95% ci [1.24-1.53]), depression (pr= 1.88 95% ci [1.80-1 .97]) and vitamin B12 deficiency (pr = 1.10 95% ci [1.01-1.20]). Conclusions: In the present study, an association was found between a low level of vitamin B12 and cognitive deterioration in older adults.

3.
Int. j. morphol ; 41(1): 210-215, feb. 2023. ilus
Article in English | LILACS | ID: biblio-1430505

ABSTRACT

SUMMARY: Apocrine glands are sweat glands that are located in the skin of the dog. Anal sac apocrine, circunanal apocrine, and mammary glands are considered modified apocrine structures, and there are about nine possible types of neoplasms and other tumors in the apocrine glands of the dog and cat, including cysts, adenoma, carcinoma, and adenocarcinoma. Thus, it is important to provide new markers to characterize these glands to improve the histopathological diagnosis. In this article, we describe the distribution of kallikrein- related peptidases 5, 7, 8, and 10 in the normal apocrine glands of the dog's skin. These proteases have been shown to play a fundamental role in the homeostasis of the human skin barrier but have been scarcely studied in canine skin.


Las glándulas apocrinas son glándulas sudoríparas que se encuentran en la piel del perro. Las glándulas apocrinas del saco anal, apocrinas circunanales y mamarias se consideran estructuras apocrinas modificadas, y existen alrededor de nueve tipos posibles de neoplasias y otros tumores en las glándulas apocrinas del perro y el gato, incluidos quistes, adenoma, carcinoma y adenocarcinoma. Por lo tanto, es importante proporcionar nuevos marcadores para caracterizar estas glándulas para mejorar el diagnóstico histopatológico. En este artículo, describimos la distribución de las peptidasas 5, 7, 8 y 10 relacionadas con la calicreína en las glándulas apocrinas normales de la piel del perro. Se ha demostrado que estas proteasas desempeñan un papel fundamental en la homeostasis de la barrera de la piel humana, pero apenas se han estudiado en la piel canina.


Subject(s)
Animals , Dogs , Apocrine Glands/metabolism , Apocrine Glands/chemistry , Kallikreins/analysis , Kallikreins/metabolism , Skin , Immunohistochemistry
5.
Int. j. morphol ; 40(6): 1656-1661, dic. 2022.
Article in Spanish | LILACS | ID: biblio-1421812

ABSTRACT

Los recursos educativos digitales se han transformado en un importante material de apoyo al proceso de enseñanza- aprendizaje, especialmente durante la pandemia por COVID-19. Estos corresponden a recursos de autoaprendizaje, generalmente en línea y de dominio público cuya disponibilidad inmediata a todo tipo de dispositivos electrónicos permite una rápida interacción del estudiante con materiales didácticos programados. El objetivo de este estudio fue evaluar el grado de satisfacción de cinco recursos educativos digitales, desarrollados como herramientas de apoyo para la enseñanza de la patología general, en estudiantes de carreras de pregrado del área de la salud de la Universidad Austral de Chile. Estudio descriptivo y exploratorio. Se desarrollaron cinco recursos educativos digitales donde se visualizan imágenes microscópicas correspondientes a procesos patológicos ocurridos en diferentes tejidos. Estos recursos fueron alojados en repositorios de la universidad y se encuentran actualmente disponibles en el canal de YouTube. Para conocer el grado de satisfacción, en sus aspectos pedagógicos y técnicos, se realizó una encuesta digital, anónima y voluntaria a estudiantes que cursaron asignaturas de patología, la que contempló cuatro dominios con sus respectivas preguntas: forma; control de usuario; contenido educativo y valoración global. El 94 % de los estudiantes calificaron el recurso de excelente o muy bueno y todos los dominios obtuvieron sobre el 80 % de satisfacción. Los contenidos representan lo que el recurso dice ofrecer, ayuda a resolver dudas y facilita la comprensión de la materia. El tamaño y color del texto es el adecuado y las imágenes presentan una excelente calidad y resolución. Los recursos cumplen con una alta calidad técnica y pedagógica, que asegura un gran potencial de uso para la enseñanza de la patología general, guiar el trabajo autónomo del estudiante y las actividades prácticas con el microscopio.


SUMMARY: Digital educational resources have become an important material to support the teaching-learning process, especially during the COVID-19 pandemic. These correspond to self-learning resources, generally online and the public domain, whose immediate availability to all types of electronic devices allows for rapid learner interaction with programmed didactic materials. The public domain and its immediate availability to all types of electronic devices allows a quick interaction of the student with self-explanatory didactic materials. The objective of this study was to evaluate the degree of satisfaction of five digital educational resources, developed as support tools for the teaching of general pathology, in undergraduate students of the health area of the Universidad Austral de Chile. Descriptive and exploratory study. Five digital educational resources have been developed where microscopic images corresponding to pathological processes occurring in different tissues are visualized these resources were hosted in university repositories and uploaded to the YouTube channel. To determine the degree of satisfaction, in their pedagogical and technical aspects, an anonymous and voluntary digital survey was carried out among students taking pathology courses, which included four domains with their respective questions: form; user control; educational content and overall assessment. The 94 % of the students evaluated the resource as excellent or very good and all domains obtained over 80 % satisfaction. The contents represent what the resource says it offers, helps to resolve doubts and facilitates the understanding of the subject. The size and color of the text is adequate, and the images present excellent quality and resolution. The resources developed offer a high technical and pedagogical quality, which guarantees a great potential for use in the teaching of general pathology, guiding the student's autonomous work and practical activities with the microscope.


Subject(s)
Humans , Pathology/education , Students, Health Occupations , Computer-Assisted Instruction/methods , Education, Medical, Undergraduate/methods , Teaching Materials , Surveys and Questionnaires
6.
Rev. argent. cir ; 114(3): 142-452, set. 2022. graf
Article in Spanish | LILACS, BINACIS | ID: biblio-1422928

ABSTRACT

RESUMEN Antecedentes: la pandemia por COVID-19 plantea un desafío inédito en la educación quirúrgica mundial. La falta de actividad práctica, fruto de las suspensiones y restricciones, pone en jaque la capacidad de los programas de entrenamiento de ajustarse a los estándares de idoneidad requeridos para el ejercicio de la especialidad. Objetivo: comparar la actividad quirúrgica de los residentes antes y durante la cuarentena, y describir los cambios de roles asistenciales y de las tácticas para su formación. Material y métodos: observacional, descriptivo, retrospectivo. Se registraron las ciru-gías realizadas por residentes en los períodos marzo 2019-febrero 2020 (Prepandemia) y marzo 2020-febrero 2021 (Intrapandemia). Se compararon la cantidad y tipo de procedimientos, así como el año de la residencia. Se analizó también el porcentaje de variación en las consultas de consultorios externos. Resultados: se experimentó una reducción global del número de operaciones del 59% (n = 368 vs. n = 152). Los procedimientos estéticos programados disminuyeron un 64%. En cirugía reconstructiva hubo una caída del 55%: tumores de piel -64%, reconstrucción mamaria -54%, reconstrucción de miembro -40%, reconstrucción cabeza y cuello -13%. En las reconstrucciones interdisciplinarias llevadas adelante con otros Servicios se observó un comportamiento dispar. La atención ambulatoria en consultorios externos experimentó una disminución del 50% (n = 2603 vs. n = 1308) en las consultas presenciales. Conclusiones: durante la cuarentena se registró una marcada disminución en todos los tipos de actividad quirúrgica y asistencial de los residentes de cirugía plástica, lo que influirá en su formación y plantea un desafío para minimizar ese impacto.


ABSTRACT Background: The COVID-19 pandemic poses an unprecedented challenge to surgical education worldwide. The lack of hands-on activity, due to suspensions and restrictions, jeopardizes the ability of training programs to meet the competence standards required for the practice of the specialty. Objective: To compare residents' surgical activity before and during the lockdown, and describe the changes in healthcare roles and training strategies. Material and Methods: We conducted a descriptive, observational and retrospective study. The surgeries performed by residents during pre-pandemic (March 2019-February 2020) and intrapandemic (March 2020-February 2021) periods were recorded. The number and type of procedures and the year of the residency program were compared in both periods. The percent change in outpatient consultations was also analyzed. Results: The total number of plastic surgery procedures was reduced by 59% (n = 368 vs. n = 152). Scheduled cosmetic procedures decreased by 64%. Reconstructive procedures decreased by 55%: skin tumors -64%, breast reconstruction -54%, extremity reconstruction -40%, head and neck reconstruction -13%. Multidisciplinary reconstructions performed with other specialists showed different patterns. Face-to-face consultations decreased by 50% (n = 2603 vs. n = 1308). Conclusions: During the lockdown, there was a marked decrease in all the types of surgical and healthcare activities among residents in plastic surgery which will influence their training, posing a challenge to minimize this impact.


Subject(s)
Humans , Plastic Surgery Procedures/statistics & numerical data , Medical Staff, Hospital/education , Quarantine , Epidemiology, Descriptive , Retrospective Studies , Plastic Surgery Procedures/education , Education, Distance , COVID-19 , Internship and Residency
7.
Pediátr. Panamá ; 51(2): 46-59, sept 2022.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1392081

ABSTRACT

Introducción. La neumonía adquirida en la comunidad complicada (CCAP) se caracteriza por una enfermedad grave, hospitalización y un curso prolongado. Las complicaciones de la neumonía se produ­cen cuando la infección no se limita al parén­quima pulmonar, sino que se extiende a áreas vecinas, o cuando el desarrollo de la infección es más complejo que el habitual por diferentes motivos. Estas complicaciones pulmonares suponen solo el 1% al 3% de las mismas, pero este porcentaje aumenta a casi un 40% en caso de precisar ingreso hospi­talario, por lo que se considera una patología fundamentalmente hospitalaria. Objetivo. El propósito de este estudio fue analizar las complicaciones de la neumonía bacteriana adquirida en la comunidad y describir sus características epidemiológicas, clínicas y etiológicas en el periodo de estudio.Material y método. Este es un estudio retrospectivo y descriptivo de las neumonías bacterianas complicadas y sus características en el Hospital del Niño Dr. José Renán Esquivel. Se realizó la búsqueda de los expedientes clínicos de los pacientes con diagnóstico de egreso de neumonía bacteriana adquirida en la comunidad complicada con derrame pleural, neumotórax, pioneumotórax, neumonía necrotizante y absceso pulmonar en el periodo del 1 de enero de 2015 al 31 de diciembre de 2020.Todos los expedientes médicos recuperados se analizaron para obtener información de las complicaciones de la neumonía bacteriana adquirida en la comunidad con relación a datos epidemiológicos, frecuencia, características, tratamiento y evolución clínica. Resultados. De acuerdo con los datos obtenidos de los boletines estadísticos del Hospital Del Niño Dr. José Renán Esquivel para el periodo comprendido entre el 1 de enero de 2015 al 31 de diciembre de 2020 se encontraron 2519 neumonías bacterianas, correspondiendo al 30% de las neumonías. De las neumonías bacterianas, 277 casos de neumonía complicada cumplieron los criterios de inclusión representando un 11% de las neumonías bacterianas. La complicación más frecuente, en todos los grupos de edad, fue el derrame pleural paraneumónico con una frecuencia de 170 casos (61%). La edad promedio de los pacientes con neumonías complicadas fue de 51.7 meses (rango de 27 días a 164 meses) y el grupo de 1 ­ 4 años fue el más afectado presentando 118 (43%) casos de complicaciones. La duración promedio de hospitalización fue de 14.8 días con un rango de 9- 38 días. Los pacientes recibieron antibióticos endovenosos de amplio espectro siendo el tratamiento empírico inicial más utilizado ceftriaxona más clindamicina. La duración promedio del tratamiento con antibióticos fue de 12.7 días con un rango de 10 a 25 días y varió de acuerdo con el tipo de complicación. Se reportaron 68 cultivos positivos, 39 en muestras de líquido pleural y 29 en hemocultivos. Encontramos que el rendimiento de los cultivos bacterianos fue mayor en los cultivos de líquido pleural en comparación con los hemocultivos, 28% vs 10% respectivamente. Los patógenos más frecuentemente aislados fueron el Staphylococcus aureus en 34 (50 %) pacientes, el Streptococcus pneumoniae en 21 (31%) pacientes y el Haemophilus influenzae en 6 (9%) pacientes en los 68 cultivos positivos. Conclusiones. El grupo de 1 ­ 4 años es el más afectado presentando 118 (43%) casos de complicaciones. El derrame pleural es la complicación más frecuente de la neumonía bacteriana adquirida en la comunidad. Se reportaron 68 cultivos positivos y el rendimiento fue mayor en los cultivos de líquido pleural en comparación con los hemocultivos. Los patógenos más frecuentemente aislados fueron el Staphylococcus aureus y el Streptococcus pneumoniae. La mayoría de los pacientes se recuperaron a pesar de la importante morbilidad. (provisto por Infomedic International)


Introduction. Complicated community-acquired pneumonia (CCAP) is characterized by severe illness, hospitalization, and a long course. The complications of pneumonia occur when the infection is not limited to the lung parenchyma, but spreads to neighboring areas, or when the development of the infection is more complex than usual for different reasons. These pulmonary complications account for only 1% to 3% of them, but this percentage increases to almost 40% if hospital admission is required, which is why it is considered a fundamentally hospital pathology.   Objective. The purpose of this study was to analyze the complications of community-acquired bacterial pneumonia and describe its epidemiological, clinical, and etiological characteristics in the study period. Material and method. This is a retrospective and descriptive study of complicated bacterial pneumonias and their characteristics at the Hospital del Niño Dr. José Renán Esquivel. A search was made of the clinical records of patients with a diagnosis of discharge from community-acquired bacterial pneumonia complicated by pleural effusion, pneumothorax, pioneumothorax, necrotizing pneumonia and lung abscess in the period from January 1, 2015 to December 31, 2020. All medical records retrieved were analyzed to obtain information on the complications of community-acquired bacterial pneumonia in relation to epidemiological data, frequency, characteristics, treatment, and clinical evolution. Results. According to the data obtained from the statistical bulletins of the Hospital Del Niño Dr. José Renán Esquivel for the period from January 1, 2015 to December 31, 2020, 2,519 bacterial pneumonias were found, corresponding to 30% of pneumonia. Of the bacterial pneumonias, 277 cases of complicated pneumonia met the inclusion criteria, representing 11% of the bacterial pneumonia. The most frequent complication, in all age groups, was parapneumonic pleural effusion with a frequency of 170 cases (61%). The average age of patients with complicated pneumonia was 51.7 months (range from 27 days to 164 months) and the 1-4-year-old group was the most affected, presenting 118 (43%) cases of complications. The average length of hospitalization was 14.8 days with a range of 9-38 days. Patients received broad-spectrum intravenous antibiotics, the most widely used initial empirical treatment being ceftriaxone plus clindamycin. The average duration of antibiotic treatment was 12.7 days with a range of 10 to 25 days and varied according to the type of complication. 68 positive cultures were reported, 39 in pleural fluid samples and 29 in blood cultures. We found that the yield of bacterial cultures was higher in pleural fluid cultures compared to blood cultures, 28% vs 10% respectively. The most frequently isolated pathogens were Staphylococcus aureus in 34 (50%) patients, Streptococcus pneumoniae in 21 (31%) patients, and Haemophilus influenzae in 6 (9%) patients in the 68 positive cultures. Conclusions. The 1­4-year-old group is the most affected, presenting 118 (43%) cases of complications. Pleural effusion is the most common complication of community-acquired bacterial pneumonia. 68 positive cultures were reported positive, and the yield was higher in pleural fluid cultures compared to blood cultures. The most frequently isolated pathogens were Staphylococcus aureus and Streptococcus pneumoniae. Most of the patients recovered despite significant morbidity. (provided by Infomedic International)

8.
MHSalud ; 19(1)jun. 2022.
Article in English | LILACS, SaludCR | ID: biblio-1386161

ABSTRACT

Abstract There is currently an increase in inertial flywheel application in strength training; thus, it must be monitored by an accurate and reliable device. The present study tested: (1) the accuracy of an inertial measurement device (IMU) to correctly measure angular velocity and (2) its inter-unit reliability for the measurement of external load. The analysis was performed using Pearson Correlation and Intraclass Correlation Coefficient (ICC). The IMU accuracy was tested using Bland-Altman and the reliability with the coefficient of variation (CV). Ten elite-level football players performed ten series of 5 repetitions in a one-hand standing row exercise (5 series with each arm). A nearly perfect accuracy (ICC=.999) and a very good between-device reliability (Bias=-.010; CV=.017%) was found. IMU is a reliable and valid device to assess angular velocity in inertial flywheel workout objectively.


Resumen Actualmente, hay un aumento en la utilización de la polea cónica en el entrenamiento de fuerza; por lo tanto, es necesario monitorearlo con un dispositivo preciso y confiable. El presente estudio probó: (1) la precisión de un dispositivo de medición inercial (IMU), para medir correctamente la velocidad angular y (2) su confiabilidad entre unidades para la medición de carga externa. El análisis se realizó utilizando la correlación de Pearson y el Coeficiente de Correlación Intra-clase (CCI). La precisión de la IMU se probó usando Bland-Altman y la confiabilidad con el Coeficiente de Variación (CV). Diez jugadores de fútbol de nivel élite realizaron 10 series de 5 repeticiones en un ejercicio de fila de pie con una mano (5 series con cada brazo). Se encontró una precisión casi perfecta (ICC = .999) y una muy buena confiabilidad entre dispositivos (Sesgo = -. 010; CV = .017%). IMU´s es un dispositivo confiable y válido para evaluar objetivamente la velocidad angular en el entrenamiento inercial de la polea cónica.


Resumo Atualmente, há um aumento na utilização da polia cônica no treinamento de força; portanto, é necessário monitorá-lo com um dispositivo preciso e confiável. O presente estudo testou: (1) a precisão de um dispositivo de medição inercial (IMU), para medir corretamente a velocidade angular e (2) sua confiabilidade interunidades para medição de carga externa. A análise foi realizada por meio da correlação de Pearson e do Coeficiente de Correlação Intraclasse (ICC). A precisão do IMU foi testada usando Bland-Altman e a confiabilidade com o Coeficiente de Variação (CV). Dez jogadores de futebol de elite realizaram 10 séries de 5 repetições em um exercício de linha em pé com uma mão (5 séries com cada braço). Foi encontrado uma precisão quase perfeita (ICC = 0,999) e confiabilidade entre dispositivos muito boa (Bias = - 0,010; CV = 0,017%). IMU's é um dispositivo confiável e válido para avaliar objetivamente a velocidade angular no treinamento inercial da polia cônica.


Subject(s)
Humans , Technology/instrumentation , Weight Lifting , Attitude
9.
Thanh-N. NGUYEN; Muhammad-M. QURESHI; Piers KLEIN; Hiroshi YAMAGAMI; Mohamad ABDALKADER; Robert MIKULIK; Anvitha SATHYA; Ossama-Yassin MANSOUR; Anna CZLONKOWSKA; Hannah LO; Thalia-S. FIELD; Andreas CHARIDIMOU; Soma BANERJEE; Shadi YAGHI; James-E. SIEGLER; Petra SEDOVA; Joseph KWAN; Diana-Aguiar DE-SOUSA; Jelle DEMEESTERE; Violiza INOA; Setareh-Salehi OMRAN; Liqun ZHANG; Patrik MICHEL; Davide STRAMBO; João-Pedro MARTO; Raul-G. NOGUEIRA; Espen-Saxhaug KRISTOFFERSEN; Georgios TSIVGOULIS; Virginia-Pujol LEREIS; Alice MA; Christian ENZINGER; Thomas GATTRINGER; Aminur RAHMAN; Thomas BONNET; Noémie LIGOT; Sylvie DE-RAEDT; Robin LEMMENS; Peter VANACKER; Fenne VANDERVORST; Adriana-Bastos CONFORTO; Raquel-C.T. HIDALGO; Daissy-Liliana MORA-CUERVO; Luciana DE-OLIVEIRA-NEVES; Isabelle LAMEIRINHAS-DA-SILVA; Rodrigo-Targa MARTÍNS; Letícia-C. REBELLO; Igor-Bessa SANTIAGO; Teodora SADELAROVA; Rosen KALPACHKI; Filip ALEXIEV; Elena-Adela CORA; Michael-E. KELLY; Lissa PEELING; Aleksandra PIKULA; Hui-Sheng CHEN; Yimin CHEN; Shuiquan YANG; Marina ROJE-BEDEKOVIC; Martin ČABAL; Dusan TENORA; Petr FIBRICH; Pavel DUŠEK; Helena HLAVÁČOVÁ; Emanuela HRABANOVSKA; Lubomír JURÁK; Jana KADLČÍKOVÁ; Igor KARPOWICZ; Lukáš KLEČKA; Martin KOVÁŘ; Jiří NEUMANN; Hana PALOUŠKOVÁ; Martin REISER; Vladimir ROHAN; Libor ŠIMŮNEK; Ondreij SKODA; Miroslav ŠKORŇA; Martin ŠRÁMEK; Nicolas DRENCK; Khalid SOBH; Emilie LESAINE; Candice SABBEN; Peggy REINER; Francois ROUANET; Daniel STRBIAN; Stefan BOSKAMP; Joshua MBROH; Simon NAGEL; Michael ROSENKRANZ; Sven POLI; Götz THOMALLA; Theodoros KARAPANAYIOTIDES; Ioanna KOUTROULOU; Odysseas KARGIOTIS; Lina PALAIODIMOU; José-Dominguo BARRIENTOS-GUERRA; Vikram HUDED; Shashank NAGENDRA; Chintan PRAJAPATI; P.N. SYLAJA; Achmad-Firdaus SANI; Abdoreza GHOREISHI; Mehdi FARHOUDI; Elyar SADEGHI-HOKMABADI; Mazyar HASHEMILAR; Sergiu-Ionut SABETAY; Fadi RAHAL; Maurizio ACAMPA; Alessandro ADAMI; Marco LONGONI; Raffaele ORNELLO; Leonardo RENIERI; Michele ROMOLI; Simona SACCO; Andrea SALMAGGI; Davide SANGALLI; Andrea ZINI; Kenichiro SAKAI; Hiroki FUKUDA; Kyohei FUJITA; Hirotoshi IMAMURA; Miyake KOSUKE; Manabu SAKAGUCHI; Kazutaka SONODA; Yuji MATSUMARU; Nobuyuki OHARA; Seigo SHINDO; Yohei TAKENOBU; Takeshi YOSHIMOTO; Kazunori TOYODA; Takeshi UWATOKO; Nobuyuki SAKAI; Nobuaki YAMAMOTO; Ryoo YAMAMOTO; Yukako YAZAWA; Yuri SUGIURA; Jang-Hyun BAEK; Si-Baek LEE; Kwon-Duk SEO; Sung-Il SOHN; Jin-Soo LEE; Anita-Ante ARSOVSKA; Chan-Yong CHIEH; Wan-Asyraf WAN-ZAIDI; Wan-Nur-Nafisah WAN-YAHYA; Fernando GONGORA-RIVERA; Manuel MARTINEZ-MARINO; Adrian INFANTE-VALENZUELA; Diederik DIPPEL; Dianne-H.K. VAN-DAM-NOLEN; Teddy-Y. WU; Martin PUNTER; Tajudeen-Temitayo ADEBAYO; Abiodun-H. BELLO; Taofiki-Ajao SUNMONU; Kolawole-Wasiu WAHAB; Antje SUNDSETH; Amal-M. AL-HASHMI; Saima AHMAD; Umair RASHID; Liliana RODRIGUEZ-KADOTA; Miguel-Ángel VENCES; Patrick-Matic YALUNG; Jon-Stewart-Hao DY; Waldemar BROLA; Aleksander DĘBIEC; Malgorzata DOROBEK; Michal-Adam KARLINSKI; Beata-M. LABUZ-ROSZAK; Anetta LASEK-BAL; Halina SIENKIEWICZ-JAROSZ; Jacek STASZEWSKI; Piotr SOBOLEWSKI; Marcin WIĄCEK; Justyna ZIELINSKA-TUREK; André-Pinho ARAÚJO; Mariana ROCHA; Pedro CASTRO; Patricia FERREIRA; Ana-Paiva NUNES; Luísa FONSECA; Teresa PINHO-E-MELO; Miguel RODRIGUES; M-Luis SILVA; Bogdan CIOPLEIAS; Adela DIMITRIADE; Cristian FALUP-PECURARIU; May-Adel HAMID; Narayanaswamy VENKETASUBRAMANIAN; Georgi KRASTEV; Jozef HARING; Oscar AYO-MARTIN; Francisco HERNANDEZ-FERNANDEZ; Jordi BLASCO; Alejandro RODRÍGUEZ-VÁZQUEZ; Antonio CRUZ-CULEBRAS; Francisco MONICHE; Joan MONTANER; Soledad PEREZ-SANCHEZ; María-Jesús GARCÍA-SÁNCHEZ; Marta GUILLÁN-RODRÍGUEZ; Gianmarco BERNAVA; Manuel BOLOGNESE; Emmanuel CARRERA; Anchalee CHUROJANA; Ozlem AYKAC; Atilla-Özcan ÖZDEMIR; Arsida BAJRAMI; Songul SENADIM; Syed-I. HUSSAIN; Seby JOHN; Kailash KRISHNAN; Robert LENTHALL; Kaiz-S. ASIF; Kristine BELOW; Jose BILLER; Michael CHEN; Alex CHEBL; Marco COLASURDO; Alexandra CZAP; Adam-H. DE-HAVENON; Sushrut DHARMADHIKARI; Clifford-J. ESKEY; Mudassir FAROOQUI; Steven-K. FESKE; Nitin GOYAL; Kasey-B. GRIMMETT; Amy-K. GUZIK; Diogo-C. HAUSSEN; Majesta HOVINGH; Dinesh JILLELA; Peter-T. KAN; Rakesh KHATRI; Naim-N. KHOURY; Nicole-L. KILEY; Murali-K. KOLIKONDA; Stephanie LARA; Grace LI; Italo LINFANTE; Aaron-I. LOOCHTAN; Carlos-D. LOPEZ; Sarah LYCAN; Shailesh-S. MALE; Fadi NAHAB; Laith MAALI; Hesham-E. MASOUD; Jiangyong MIN; Santiago ORGETA-GUTIERREZ; Ghada-A. MOHAMED; Mahmoud MOHAMMADEN; Krishna NALLEBALLE; Yazan RADAIDEH; Pankajavalli RAMAKRISHNAN; Bliss RAYO-TARANTO; Diana-M. ROJAS-SOTO; Sean RULAND; Alexis-N. SIMPKINS; Sunil-A. SHETH; Amy-K. STAROSCIAK; Nicholas-E. TARLOV; Robert-A. TAYLOR; Barbara VOETSCH; Linda ZHANG; Hai-Quang DUONG; Viet-Phuong DAO; Huynh-Vu LE; Thong-Nhu PHAM; Mai-Duy TON; Anh-Duc TRAN; Osama-O. ZAIDAT; Paolo MACHI; Elisabeth DIRREN; Claudio RODRÍGUEZ-FERNÁNDEZ; Jorge ESCARTÍN-LÓPEZ; Jose-Carlos FERNÁNDEZ-FERRO; Niloofar MOHAMMADZADEH; Neil-C. SURYADEVARA,-MD; Beatriz DE-LA-CRUZ-FERNÁNDEZ; Filipe BESSA; Nina JANCAR; Megan BRADY; Dawn SCOZZARI.
Journal of Stroke ; : 256-265, 2022.
Article in English | WPRIM | ID: wpr-938173

ABSTRACT

Background@#and Purpose Recent studies suggested an increased incidence of cerebral venous thrombosis (CVT) during the coronavirus disease 2019 (COVID-19) pandemic. We evaluated the volume of CVT hospitalization and in-hospital mortality during the 1st year of the COVID-19 pandemic compared to the preceding year. @*Methods@#We conducted a cross-sectional retrospective study of 171 stroke centers from 49 countries. We recorded COVID-19 admission volumes, CVT hospitalization, and CVT in-hospital mortality from January 1, 2019, to May 31, 2021. CVT diagnoses were identified by International Classification of Disease-10 (ICD-10) codes or stroke databases. We additionally sought to compare the same metrics in the first 5 months of 2021 compared to the corresponding months in 2019 and 2020 (ClinicalTrials.gov Identifier: NCT04934020). @*Results@#There were 2,313 CVT admissions across the 1-year pre-pandemic (2019) and pandemic year (2020); no differences in CVT volume or CVT mortality were observed. During the first 5 months of 2021, there was an increase in CVT volumes compared to 2019 (27.5%; 95% confidence interval [CI], 24.2 to 32.0; P<0.0001) and 2020 (41.4%; 95% CI, 37.0 to 46.0; P<0.0001). A COVID-19 diagnosis was present in 7.6% (132/1,738) of CVT hospitalizations. CVT was present in 0.04% (103/292,080) of COVID-19 hospitalizations. During the first pandemic year, CVT mortality was higher in patients who were COVID positive compared to COVID negative patients (8/53 [15.0%] vs. 41/910 [4.5%], P=0.004). There was an increase in CVT mortality during the first 5 months of pandemic years 2020 and 2021 compared to the first 5 months of the pre-pandemic year 2019 (2019 vs. 2020: 2.26% vs. 4.74%, P=0.05; 2019 vs. 2021: 2.26% vs. 4.99%, P=0.03). In the first 5 months of 2021, there were 26 cases of vaccine-induced immune thrombotic thrombocytopenia (VITT), resulting in six deaths. @*Conclusions@#During the 1st year of the COVID-19 pandemic, CVT hospitalization volume and CVT in-hospital mortality did not change compared to the prior year. COVID-19 diagnosis was associated with higher CVT in-hospital mortality. During the first 5 months of 2021, there was an increase in CVT hospitalization volume and increase in CVT-related mortality, partially attributable to VITT.

10.
Rev. chil. infectol ; 38(6): 745-753, dic. 2021. ilus, tab
Article in Spanish | LILACS | ID: biblio-1388315

ABSTRACT

INTRODUCCIÓN: La enfermedad COVID-19, además de presentar síntomas respiratorios, puede afectar otros órganos como la piel. Al momento, se han descrito cinco variantes clínicas de manifestaciones cutáneas por COVID-19. Pocos reportes abordan el tema de la gravedad de las dermatosis cutáneas de COVID-19 y el pronóstico. OBJETIVO: Describir patrones clínicos e histológicos de dermatosis en pacientes con COVID-19. Pacientes y MÉTODOS: Es una cohorte para pacientes del IMSS-T1 en León, Guanajuato, México, entre septiembre 2020 y enero 2021. Identificamos pacientes con dermatosis asociada a COVID-19 desde su ingreso hospitalario y aquellos que la desarrollaron durante su estancia. Se les invitó a participar para evaluación clínica y toma de biopsia que fueron descritas por un patólogo experto. RESULTADOS: La frecuencia de las dermatosis por COVID-19 fue de 15,7%. Los que desarrollaron las lesiones durante su estancia hospitalaria presentaron mayor morbi-mortalidad (p = 0,001). Las lesiones vaso-oclusivas fueron las más diagnosticadas y asociadas con mayor mortalidad (p = 0,003). Histológicamente el hallazgo más común fue trombosis superficial y profunda (58%). CONCLUSIONES: Los pacientes que desarrollaron las lesiones durante su hospitalización y aquellos con lesiones vaso-oclusivas tuvieron la mayor morbi-mortalidad. Las lesiones vaso-oclusivas pueden ser un factor de mal pronóstico en pacientes con COVID-19.


BACKGROUND: COVID-19 disease, besides presenting respiratory manifestations, can affect other organs such as kidneys, gastrointestinal system, heart, and skin. So far, five clinical variants of dermatoses have been described. Few reports discuss the severity associated with the cutaneous manifestations of COVID-19 and the prognosis. AIM: To describe the clinical and histopathological patterns of dermatoses in patients with COVID-19 infection. PATIENTS AND METHODS: Prospective cohort study conducted in patients admitted to "IMSS T1" in Leon, Guanajuato, Mexico from September 2020 to January 2021. We identified those with COVID-19 dermatosis from the moment they were admitted; and those who developed them during hospitalization. Patients were invited to participate for a clinical evaluation and biopsy. The biopsies were described by an expert pathologist. RESULTS: The frequency of dermatological lesions was 15.7%. Those who developed dermatosis during their hospital stay presented higher mortality (p = 0.001) and severity of COVID-19 (p = 0.001) Vasoocclusive lesions were the most frequent in the hospital setting, and were associated to higher mortality (p = 0.003). The most frequent histopathological feature was superficial and deep thrombosis (58%). CONCLUSIONS: Patients who developed dermatologic lesions during hospitalization and those with vaso-occlusive dermatoses had higher morbi-mortality. Vaso-occlusive lesions could be considered as a poor prognostic factor.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Skin Diseases/pathology , COVID-19/pathology , Prospective Studies , Hospitalization , Length of Stay
11.
Rev. argent. cardiol ; 89(3): 183-188, jun. 2021. graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1356873

ABSTRACT

RESUMEN Introducción: El diagnóstico de hipertensión arterial (HTA) se realiza por la toma de la presión arterial (PA) en el consultorio médico (C) o en enfermería (E). Es frecuente aproximar los valores obtenidos a múltiplos de 10. Esto puede causar imprecisiones en el diagnóstico y el control de la HTA. Objetivo: Determinar cuántos registros de PA terminaban en cero en las mediciones realizadas en E y en C en dos centros de atención primaria de la salud de la ciudad de Salta. Material y métodos: Se efectuó un estudio descriptivo, transversal, de febrero a diciembre de 2018. Se utilizó un tensiómetro digital. A cada paciente se le midió la PA dos veces, primero en E y luego en C. Se utilizaron las pruebas de Chi2 y de Wilcoxon. Resultados: Se estudiaron 311 individuos, 60,77% mujeres. Edad media: 56,15 ± 13,8 años. Los registros terminados en cero tuvieron las siguientes frecuencias: PA sistólica en E: 36%; PA diastólica en E: 40,51%; PA sistólica en C: 11,58%; PA diastólica en C: 7,72% (p <0,0001). La PA sistólica y diastólica terminaron simultáneamente en cero en el 30,87% de los casos cuando se midieron en E y en el 0,64% de los casos cuando se midieron en C (p <0,0001). Conclusiones: La PA sistólica y la PA diastólica terminaron en cero con una frecuencia 3 y 5 veces mayor en E que en C, respectivamente, y la frecuencia de registros de PA sistólica y diastólica coincidentemente terminados en cero fue 48 veces mayor en E que en C. Estos resultados refuerzan la necesidad de una capacitación permanente para mejorar el registro en la medición de la PA.


ABSTRACT Background: The diagnosis of hypertension is established by blood pressure (BP) measurements in doctor (DO) or nursing offices (NO). Frecuently BP measurements are recorded as multiples of ten. This can lead to inaccuracy in diagnosis and control of hypertension. Objetive: To determine the percentage of BP measurements ending in zero in DO and NO, in the records of two health primary centers of Salta city. Methods: Observational study from february to december of 2018. Digital blood pressure monitor was used. Each patient BP was measured twice, first in NO and then in DO. Data were analyzed using the Chi2 and Wilcoxon tests. Results: 311 indivuals were enrolled, 60,77% were female. The average age was 56,15 ± 13,8 years. In NO the systolic BP and diastolic BP ending in zero were 36 and 40,51% respectively, while in DO were 11,58 and 7,72% (p <0,0001). The systolic BP and diastolic BP ending in zero simultaneously in NO was 30,87%, while in DO was 0,64% (p <0,0001). Conclusions: The systolic BP and the diastolic BP records ending in zero were three and five times more frequent in NO than in DO. The systolic BP and diastolic BP ending in zero simultaneously in NO were forty-eight times more frequent than in DO. These results reinforce the need of health personnel permanent training to improve precision for measuring and recording BP in medical centers.

12.
Medicina (B.Aires) ; 81(3): 329-336, jun. 2021. graf
Article in Spanish | LILACS | ID: biblio-1346467

ABSTRACT

Resumen El índice PROFUND se desarrolló y validó para predecir mortalidad a 12 meses en pacientes pluripatológicos. Sin embargo, su valor potencial para predecir mortalidad intrahospitalaria no ha sido suficientemente estudiado. Se evaluó la capacidad del índice PROFUND en comparación con la proteína C re activa (PCR), la albúmina, y el ancho de distribución eritrocitaria (ADE) para predecir mortalidad intrahospitalaria, mediante el análisis posterior de una cohorte prospectiva de 111 pacientes pluripatológicos internados en clínica médica. La edad promedio fue 75.8 ± 9.3 años. La mortalidad intrahospitalaria fue de 17% (19 pacientes). La mediana (RIQ) del índice PROFUND, albúmina, PCR y ADE en los fallecidos y sobrevivientes fue 12 (4) y 6 (7) p< 0.0001, 2.5 (0.4) y 2.6 (0.8) p 0.295, 58 (64) y 40 (60) p 0.176, 14.5 (2) y 14.6 (3) p 0.523, respectivamente. El análisis logístico multivariado mostró que el índice PROFUND se asocia con mortalidad intrahospitalaria (p 0.0003). El riesgo de fallecer durante la internación es 20% mayor por cada punto que se incrementa el índice PROFUND (OR 1.2, IC95% 1.1-1.4). El área bajo la curva de las características operativas del receptor (AUC-ROC) del índice PROFUND para predecir mortalidad durante la internación (0.760, IC95% 0.628-0.891) fue mayor a la del ADE, PCR y albúmina (0.494 IC95% 0.364-0.624 p 0.012; 0.583 IC95% 0.437-0.728 p 0.028; 0.621 0.494-0.748 p 0.109, respectivamente). El índice PROFUND se asocia a mortalidad intrahospitalaria, con una mayor capacidad predictiva que los biomarcadores estudiados, lo cual se sumaría a su valor pronóstico a largo plazo en pacientes pluripatológicos.


Abstract The PROFUND index was developed and valid to predict mortality at 12 months in polypathological patients (PP). However, its potential value for predicting in-hospital mortality has not been sufficiently studied. The ability of the PROFUND index in comparison with C-reactive protein (CRP), albumin, and red blood cell distribu tion width (RDW) to predict in-hospital mortality was evaluated through the subsequent analysis of a prospective cohort of 111 multiple pathological patients admitted to the clinic medical. The mean age was 75.8 ± 9.3 years. In-hospital mortality was 17% (19 patients). The median (IQR) of the PROFUND index, albumin, CRP and ADE in the deceased and survivors was 12 (4) and 6 (7) p < 0.0001, 2.5 (0.4) and 2.6 (0.8) p 0.295, 58 (64) and 40 (60) p 0.176, 14.5 (2) and 14.6 (3) p 0.523, respectively. The multivariate logistic analysis showed that the PROFUND index is associated with in-hospital mortality (p 0.0003). The risk of dying during hospitalization is 20% higher for each point that the PROFUND index increases (OR 1.2, 95% CI 1.1-1.4). The area under the curve the receiver operating characteristic (AUC-ROC) of the PROFUND index to predict mortality during hospitalization (0.760, 95% CI 0.628-0.891) was higher than that of the RDW, CRP and albumin (0.494 95% CI 0.364-0.624 p 0.012; 0.583 95% CI 0.437-0.728 p 0.028; 0.621 0.494-0.748 p 0.109, respectively). The PROFUND index is associated with in-hospital mortality, with a greater predictive capacity than the biomarkers studied, which would add to its long-term prognostic value in multiple pathological patients.


Subject(s)
Humans , Aged , Aged, 80 and over , Erythrocyte Indices , Hospitalization , Prognosis , Prospective Studies , Retrospective Studies , ROC Curve , Cohort Studies , Hospital Mortality
13.
Medicina (B.Aires) ; 80(6): 622-632, dic. 2020. graf
Article in Spanish | LILACS | ID: biblio-1250284

ABSTRACT

Resumen El índice PROFUND es una de las puntuaciones pronósticas sugeridas en pacientes pluripatológicos (PP). A pesar del valor pronóstico de la desnutrición y su prevalencia en esta población, el mismo no incluye una variable que estime el estado nutricional. La valoración global subjetiva (VGS) es una herramienta ampliamente validada para tal fin. Se evaluó mediante un estudio prospectivo y observacional, la capacidad pronóstica de mortalidad a 12 meses del índice PROFUND y VGS en PP internados en clínica médica. Ingresaron al estudio 111 pacientes. Edad 75.8 (± 9.3) años. Índice PROFUND 7.6 (± 4.7) puntos. El 60.1% presentaba desnutrición moderada-severa por VGS. Fallecieron 66 dentro del año. En el modelo de Cox, la VGS y el índice PROFUND se asocian con mortalidad a los 12 meses (p < 0.0001 y p 0.0026 respectivamente). En los desnutridos severos, el riesgo es aproximadamente 6 veces mayor en comparación a los normonutridos (HR: 6.514, IC95% 2.826-15.016) y para un mismo nivel de VGS, el riesgo es un 10% mayor por cada punto que aumenta el índice PROFUND (HR: 1.106, IC95% 1.036-1.181). El AUC para predecir mortalidad a 12 meses del índice PROFUND y VGS fue: 0.747 (IC95%: 0.656-0.838); 0.733 (IC95%: 0.651-0.816) y al combinar las dos variables: 0.788 (IC95%: 0.703-0.872, p 0.048). Como conclusión el índice PROFUND y la VGS se asocian con mortalidad y tienen un valor pronóstico similar. La combinación de ambas herramientas permitiría establecer mejor el pronóstico y el manejo en esta compleja población


Abstract The PROFUND index is one of the suggested prognostic scores in pluripathological patients (PP). Despite the prognostic value of malnutrition and its prevalence in this population, it does not include a variable that estimates nutritional status. Subjective global assessment (SGA) is a widely validated tool for this purpose. The prognostic capacity of 12-month mortality of PROFUND index and SGA in PP admitted to a medical clinic was evaluated by a prospective and observational study. 111 patients entered the study. Age 75.8 (± 9.3) years. PROFUND index 7.6 (± 4.7) points. 60.1% had moderate-severe malnutrition due to VGS. 66 died within the year. In the Cox model, SGA and PROFUND index are associated with mortality at 12 months (p <0.0001 and p 0.0026 respectively). In severe malnutrition, the risk is approximately 6 times higher compared to normonutrition (HR: 6.514, 95% CI 2.826-15.016) and for the same level of SGA, the risk is 10% higher for each point that the PROFUND index increases (HR: 1.106, 95% CI 1.036-1.181). The AUC for predicting 12-month mortality from PROFUND index and SGA was: 0.747 (95% CI: 0.656-0.838); 0.733 (95% CI: 0.651-0.816) and when combining the two variables: 0.788 (95% CI: 0.703-0.872, p 0.048). In conclusion, PROFUND index and SGA are associated with mortality and have a similar prognostic value. The combination of both tools would allow better prognosis and management in this complex population.


Subject(s)
Humans , Malnutrition/diagnosis , Malnutrition/epidemiology , Hospitalization , Prognosis , Nutrition Assessment , Nutritional Status , Prospective Studies
14.
Rev. colomb. ciencias quim. farm ; 49(3): 822-842, Sep.-Dec. 2020. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1156319

ABSTRACT

SUMMARY The experimental data of sulfadiazine in (methanol + water), (ethanol + water) and (1-propanol + water) cosolvent mixtures at some temperatures were correlated using non-ideal solution models, namely, the modified Apelblat and Buchowski-Ksiazaczak equations and the van't Hoff equation. The calculated results agreed well with the experimental data. According to the Buchowski equation, the solubility of sulfadiazine in the three co-solvent mixtures shows important deviations from ideality, which is consistent with the literature.


RESUMEN Los datos experimentales de sulfadiazina en mezclas de cosolvente de (metanol + agua), (etanol + agua) y (1-propanol + agua) a algunas temperaturas se correlacionaron utilizando modelos de solución no ideales, a saber, las ecuaciones modificadas de Apelblat y Buchowski y la ecuación de van't Hoff. Los resultados calculados coincidieron bien con los datos experimentales. Según la ecuación de Buchowski, la solubilidad de la sulfadiazina en las tres mezclas de cosolventes muestra importantes desviaciones de la idealidad, lo que concuerda con la literatura.

15.
Rev. psicol. organ. trab ; 20(3): 1157-1165, jul.-set. 2020. ilus, tab
Article in Portuguese | LILACS-Express | LILACS, INDEXPSI | ID: biblio-1127191

ABSTRACT

Os aplicativos de economia compartilhada impulsionaram um novo modelo de trabalho e um novo perfil de trabalhador. Considerando tal realidade, o presente estudo buscou identificar os principais motivadores de engajamento como trabalhador em plataformas de mobilidade urbana, mais especificamente de compartilhamento de carona (ridesharing). Em concomitância, investigou-se a influência de fatores socioeconômicos na relevância dos diferentes motivadores. Participaram da pesquisa quarenta e três motoristas de aplicativos, por meio online, a partir do aplicativo denominado Google Formulários. Para a análise de dados foi utilizado o modelo estatístico de regressão múltipla. Nos resultados encontrados, os motivadores considerados os mais relevantes para a escolha dos participantes foram Autonomia, Renda e Horário Flexível. Dos catorze motivadores investigados, dez apresentaram interações estatisticamente significativas com aspectos socioeconômicos. Os resultados também apontam diferenças entre os motivadores considerados como mais relevantes pelos participantes, quando comparados com estudos realizados em outros países. Salienta-se, portanto, a necessidade de um olhar diferenciado para a realidade brasileira.


Sharing economy applications have boosted a new work model and worker profile. The present study aimed to identify the main worker's motivators for engagement in urban mobility platforms, specifically in ridesharing applications. The influence of socioeconomic factors on the relevance of motivators was also investigated. Data was collected using an online survey from 43 drivers who work through applications. A multiple regression model was used for data analysis. The results showed that the most important motivators indicated by the participants were autonomy, income, and having flexible schedules. 10 out of the 14 motivators studied had significant interactions with socioeconomic aspects. The results also point out differences between the motivators considered most relevant by the participants, when compared to studies carried out in other countries. Therefore, a specific approach to this topic which is compatible with the Brazilian reality is needed.


Los aplicativos de movilidad urbana impulsaron un nuevo modelo de trabajo y un nuevo perfil de trabajadores. Considerando tal realidad, este estudio buscó identificar los principales motivadores de la participación como trabajador en plataformas de movilidad urbana, más específicamente de viajes compartidos. En concomitancia, fue investigada la influencia de los factores socioeconómicos en la relevancia de los diferentes motivadores. Participaron de la pesquisa cuarenta y tres conductores de aplicativos, por medio on line, a través del aplicativo denominado Google Formulários. Para el análisis de datos, se utilizó el modelo estadístico de regresión múltiple. Según los resultados, los motivadores considerados más relevantes para los participantes fueron Autonomía, Ingresos y Horas Flexibles. De los catorce motivadores investigados, diez tuvieron interacciones estadísticamente significativas con aspectos socioeconómicos. Comparado con estudios realizados en otros países, los resultados mostraron diferencias entre los motivadores mas relevantes. Por lo tanto, se enfatiza la necesidad de una mirada diferente, ajustada a la realidad brasileña.

16.
Medicina (B.Aires) ; 80(5): 425-432, ago. 2020. graf
Article in Spanish | LILACS | ID: biblio-1287193

ABSTRACT

Resumen La pandemia de COVID-19 ha llevado a medidas de aislamiento social, restricciones laborales, fuerte campaña mediática y suspensión de las actividades médicas programadas. El objetivo de nuestro estudio fue relevar el impacto de estas medidas sobre las internaciones en Unidades de Cuidados Intensivos Cardiovasculares, con la hipótesis de que se ha generado un comportamiento social que puede disminuir la demanda de consultas, aun las de enfermedades graves. Comparamos las internaciones de marzo-abril de 2010-2019 con las del mismo bimestre de 2020 sobre la base del registro prospectivo multicéntrico Epi-Cardio® en seis instituciones, tres públicas y tres privadas, que utilizan la epicrisis computarizada para las altas. Fueron incluidos 6839 egresos de ese bimestre en los 11 años. El promedio del número de internaciones en ese bimestre del decenio 2010-19 fue 595 (intervalo de confianza 95%: 507-683) y se redujo a 348 en 2020 (caída del 46.8%, p < 0.001). En la agrupación por 11 causas de internación, la reducción observada fue: cirugía cardiovascular 72.3%, intervenciones electrofisiológicas 67.8%, síndrome coronario agudo sin elevación del ST 52.6%, angio-plastias 47.6%, arritmias 48.7%, insuficiencia cardíaca 46%, fibrilación auricular 35.7%, infarto con elevación del ST 34.7%, dolor no coronario 31.8% y otros 51.6%. Solo se incrementaron las consultas por crisis hipertensivas (89%), aunque la prevalencia fue baja. La caída observada en la internación de entidades clínicas críticas ha sido un "efecto adverso" de las medidas adoptadas ante la pandemia, con consecuencias potencialmente graves, que podrían revertirse con un ajuste de las políticas y la comunicación pública.


Abstract The COVID-19 pandemic has led to measures of social isolation, labor restrictions, a strong information campaign and the suspension of scheduled medical activities. The aim of this study was to describe the impact of these measures on the number of hospitalizations in Cardiovascular Intensive Care Units, with the hypothesis that the social behavior generated by this emergency promotes a decreased demand for medical care, even when severe cardiovascular disease is involved. We compared the number of admissions in March-April 2010-2019 versus March-April 2020, based on a prospective study including six institutions (three public and three private) that use Epi-Cardio® as a multicenter registry of cardiovascular care unit discharge. Altogether, we included 6839 patients discharged during the 11-year study period (2010-2020). The average number of patient admissions on March-April 2010-19 was 595 (CI 95%: 507-683) and decreased to 348 in 2020 (fall of 46.8%, p < 0.001). The reasons for hospitalization were classified into 11 groups and a statistically significant reduction was seen in 10 of these groups: cardiovascular surgery 72.3%, electrophysiological interventions 67.8%, non-ST acute coronary syndromes 52.6%, angioplasties 47.6%, arrhythmias 48.7%, heart failure 46%, atrial fibrillation 35.7%, ST elevation myocardial infarction 34.7%, non cardiac chest pain 31.8%, others 51.6%. Although with low prevalence, hypertensive crisis increased in 89%. The abrupt decrease observed in the number of admissions due to critical pathologies may be considered an "adverse effect" related to the measures adopted, with potentially severe consequences. This trend could be reversed by improving public communication and policy adjustment.


Subject(s)
Humans , Cardiovascular Diseases/epidemiology , Coronavirus Infections/prevention & control , Coronavirus Infections/epidemiology , Pandemics , Hospitalization/statistics & numerical data , Intensive Care Units/statistics & numerical data , Patient Admission/statistics & numerical data , Argentina/epidemiology , Pneumonia, Viral/prevention & control , Pneumonia, Viral/epidemiology , Cardiovascular Diseases/diagnosis , Prospective Studies , Betacoronavirus , SARS-CoV-2 , COVID-19
17.
Pensar mov ; 18(1)jun. 2020.
Article in English | LILACS, SaludCR | ID: biblio-1386727

ABSTRACT

Abstract The purpose of the study was to analyze the variation of running speed and heart rate in amateur runners during a marathon in a hot environment. Eighteen runners (weight: 65.2 ± 12.21 kg, height: 168.4 ± 10.6 cm, VO2max: 52.9 ± 7.1 ml/kg/min) took part of a beach-side marathon (42195 m) under a temperature of 27.8 ± 3.52 ºC and at 0-80 m altitude. Pearson's correlation showed a significant linear relationship between the increase in thermal stress index (WGBT) and the speed variation (r= 0.168, p= 0.049). In this respect, the total duration of the race revealed a direct relationship with speed (r= 0.675, p= 0.003) and heart rate (r= 0.631, p= 0.007) variation. Multiple regressions analysis showed that 61.6% of the final race time was explained by the speed variation in the 26 to 30 km course section (r 2 = 0.61; F= 26.17; p< 0.001) and 37% by the heart rate variation in the 31 to 35 km section (r 2 = 0.37; F= 10.38; p< 0.001). In conclusion, an increase in the environmental temperature provoked a decrease in running pacing, with a stronger effect in the second half of the race. Therefore, coaches should take these aspects into account in training and strategies to mitigate the impact of these conditions on the physical and physiological performance of amateur runners.


Resumo O presente estudo teve como objetivo analisar a variação da velocidade da corrida e a frequência cardíaca em corredores amadores durante uma maratona em um ambiente de alto índice térmico. Dezoito corredores amadores (peso: 65,2 ± 12,21 kg, altura: 168,4 ± 10,6 cm, VO2max: 52,9 ± 7,1 ml/kg/min) correram uma maratona (42195 m) em proximidade ao mar, sob um índice térmico de 27,8 ± 3,52 ºC e com percurso de 0-80 metros acima do nível do mar. O teste de Pearson apresentou uma correlação significativa entre o aumento do índice de estresse térmico (IBUTG) e a variação da velocidade (r= 0,168, p= 0,049). Neste sentido, a duração total da corrida apresentou uma relação direta com a velocidade (r= 0,675, p= 0,003) e a variação da frequência cardíaca (r= 0,631, p= 0,007). O tempo final da corrida se interpretou em 61,6% e 37% pela variação da velocidade de 26 a 30 km (r 2 = 0,61; F= 26,17; p< 0,001) e pela variabilidade da frequência cardíaca no lapso de 31 a 35 km (r 2 = 0,37; F= 10,38; p< 0,001), respectivamente. Em suma, o índice térmico provoca uma diminuição no ritmo da velocidade, sendo esse efeito maior na segunda metade da corrida. Devido a isso, os preparadores devem planejar treinamentos e estratégias para mitigar o impacto dessas condições no desempenho físico e fisiológico dos corredores amadores.


Resumen El objetivo del presente estudio fue analizar la variación de la velocidad de carrera y la frecuencia cardíaca en corredores aficionados durante un maratón en un entorno de alto índice térmico. Dieciocho corredores aficionados (peso: 65.2 ± 12.21 kg, altura: 168.4 ± 10.6 cm, VO2max: 52.9 ± 7.1 ml/kg/min) corrieron un maratón (42 195 m) en cercanía al mar bajo un índice térmico de 27.8 ± 3.52ºC y con recorrido de 0-80 m.s.n.m. La prueba de Pearson mostró una correlación significativa entre el aumento del índice de estrés termal (TGBH) y la variación de la velocidad (r = 0.168, p = 0.049). En este sentido, la duración total de la carrera presentó una relación directa con la velocidad (r = 0.675, p = 0.003) y la variación de la frecuencia cardíaca (r= 0.631, p = 0.007). El tiempo final de carrera se explicó en un 61.6% y 37% por la variación de la velocidad de 26 a 30 km (r 2 = 0.61; F = 26.17; p < 0.001) y por la variabilidad de la frecuencia cardíaca en el lapso de 31 a 35 km (r 2 = 0.37; F= 10.38; p < 0.001) respectivamente. En conclusión, el índice térmico provoca una disminución en el ritmo de la velocidad, este efecto mayor en la segunda mitad de la carrera. Por lo anterior, entrenadores deben planificar entrenamientos y estrategias para mitigar el impacto de estas condiciones en el desempeño físico y fisiológico de los corredores amateur.


Subject(s)
Humans , Walking Speed , Heart Rate , Hot Temperature
18.
Rev. argent. cardiol ; 88(3): 201-206, mayo 2020. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1250969

ABSTRACT

RESUMEN Introducción: La hipertensión arterial (HTA) es la primera causa de morbimortalidad cardiovascular. A menudo es una enfermedad mal controlada porque los sistemas de salud están más orientados a atender enfermedades agudas. El Ministerio de Salud de Argentina propuso un nuevo modelo de atención para pacientes hipertensos conocido como MAPEC, basado en el Modelo de cuidados crónicos. Objetivo: Evaluar el impacto de la implementación del MAPEC en el control de la presión arterial (PA), el cuidado de las medidas higiénico-dietéticas, el conocimiento de la enfermedad y la adherencia al tratamiento en pacientes hipertensos asistidos en tres centros de atención primaria de la ciudad de Salta, Argentina. Material y Métodos: Se midió la PA con tensiómetro digital automático; se evaluó el conocimiento de la HTA y la adherencia al tratamiento con los test de Batalla y Morisky-Green-Levine, respectivamente. Resultados: Se estudiaron 232 pacientes. Hubo diferencias significativas (p <0,0001) luego de la intervención en el control de la PA, el conocimiento de la enfermedad, la adherencia al tratamiento y las medidas higiénico-dietéticas. También en los promedios de PA, con una disminución de 12,97 (IC95: 9,52-16,42) mmHg en la presión sistólica y de 6,93 (IC95: 4,70-9,16) mmHg en la presión diastólica. Conclusiones: Fue evidente la mejoría en los parámetros de salud analizados en los pacientes con la implementación del MAPEC. Este modelo es de fácil aplicación y bajo costo. Además, está en consonancia con los objetivos 25×25 de la OMS, mediante los que se busca una reducción del 25% de las muertes prematuras por enfermedades cardiovasculares hacia el año 2025.


ABSTRACT Background: blood hypertension is the first cause of worldwide cardiovascular morbidity and mortality. Nevertheless, it is a poorly controlled disease, largely because health care systems are oriented to the attention of acute diseases. The Argentine Ministry of Health proposed a new care model for hypertensive patients called MAPEC, based on the Chronic Care Model. Objective: to evaluate the impact made by the implementation of MAPEC to improve the blood pressure control, the treatment adherence and changes in life style, and disease awareness, in three primary health centers of Salta city Argentine. Methods: the blood pressure was measured with automated device, Batalla and Morisky-Green-Levine were used to evaluate the disease awareness and treatment adherence, respectively. Results: 232 patients were included. After model implementation, significant difference (p<0,0001) were found in blood pressure control, disease awareness, treatment adherence and changes in life style. There was a decrease in blood pressure average with reduction of 12,97 (IC 95: 9,52-16,42) mm Hg and 6,93 (IC 95: 4,70-9,16) mm Hg in sistolic and diastolic pressure, respectively. Conclusions: there was evident improvement in the analyzed health parameters after MAPEC implementation. This can be easily adapted for primary health centers and with low cost. This is in order with WHO 25×25 target to reduce 25% cardiovascular premature deaths in 2025.

19.
Rev. Assoc. Med. Bras. (1992) ; 66(1): 36-41, Jan. 2020. tab, graf
Article in English | LILACS | ID: biblio-1091909

ABSTRACT

SUMMARY OBJECTIVE Acne vulgaris in female adolescents, when severe or accompanied by other signs of androgenization, may represent a sign of hyperandrogenemia often underdiagnosed, which will have harmful consequences for adult life. The objective of this cross-sectional and retrospective study was to demonstrate the incidence of hormonal changes in the cases of female adolescents with severe or extensive acne, with or without other signs of hyperandrogenism, and propose a hormonal research pattern which should be indicated in order to detect early hyperandrogenemia. METHODS The medical records of 38 female patients aged between 9 and 15 years old with grade II and/or III acne were analyzed. The dehydroepiandrosterone sulfate, dehydroepiandrostenedione, and androstenedione, total testosterone, and dihydrotestosterone sulfate hormones were required prior to initiation of treatment. The hormonal dosages were performed in the serum after at least 3 hours of fasting by means of radioimmunoassay tests. RESULTS Of the 38 patients included, 44.7% presented changes in androgen levels (hyperandrogenemia), and the two most frequently altered hormones were DHEA and androstenedione, with the same incidence (23.6%). CONCLUSIONS The correct and early diagnosis provides an effective and agile approach, including antiandrogen therapy, with the purpose of avoiding the reproductive and metabolic repercussions, besides controlling the inflammatory picture and avoid aesthetic complications.


RESUMO OBJETIVO A acne vulgar em adolescentes do sexo feminino, quando grave ou acompanhada de outros sinais de androgenização, pode representar um sinal de hiperandrogenemia muitas vezes subdiagnosticado, que acarretará consequências danosas para a vida adulta. O objetivo deste estudo transversal e retrospectivo foi demonstrar a incidência das alterações hormonais nos casos de adolescentes do sexo feminino com acne grave ou extensa, acompanhada ou não de outros sinais de hiperandrogenismo e propor um padrão de pesquisa hormonal que deve ser indicado com o intuito de detectar precocemente o quadro de hiperandrogenemia. MÉTODOS Foram analisados os prontuários de 38 pacientes do sexo feminino com idades entre 9 e 15 anos, portadoras de quadro de acne grau II e/ou III. Os hormônios sulfato de dehidroepiandrostenediona, dehidroepiandrostenediona, androstenediona, testosterona total e dehidrotestosterona foram solicitados antes do início do tratamento. As dosagens hormonais foram realizadas no soro após pelo menos 3 horas de jejum por meio de exames de radioimunoensaio. RESULTADOS Das 38 pacientes incluídas, 44,7% apresentaram alterações dos níveis de andrógenos (hiperandrogenemia), sendo que os dois hormônios mais frequentemente alterados foram o DHEA e androstenediona, com a mesma incidência (23,6%). CONCLUSÕES O diagnóstico correto e precoce propicia uma abordagem efetiva e ágil, incluindo a terapia antiandrogênica, com a finalidade de evitar as repercussões reprodutivas e metabólicas, além de controlar o quadro inflamatório e evitar complicações estéticas.


Subject(s)
Humans , Female , Child , Adolescent , Acne Vulgaris/blood , Hyperandrogenism/diagnosis , Androgens/blood , Severity of Illness Index , Hyperandrogenism/blood
20.
Rev. bras. cineantropom. desempenho hum ; 22: e71427, 2020. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1137249

ABSTRACT

Abstract Currently, the load quantification during training and competition in all sports is important to injury prevention, design specific training sessions, and player performance enhancement. The present study aimed to describe the external load profile of amateur-level handball players and to compare the playing position and match outcome-related differences in an official 2nd Regional Division male official match. 19 handball players were monitored by WIMU PROTM electronic performance and tracking systems (EPTS) with ultrawide-band (UWB) indoor location technology. Statistical analysis was composed of a t-student independent sample test and one-way ANOVA with Bonferroni posthoc. In amateur handball, most demands are composed of aerobic intensity displacements (<12 km/h, 76% playing time) and low-intensity impacts (<5G). Differences were found between playing positions where wingers obtained the greatest values in high-intensity actions, centers in the volume of demands, and defensive specialist players in impacts. Besides, the winning teams performed greater high-intensity demands both in displacements and speed changes. In conclusion, the present results realized the first approximation to handball amateur demands, considering the playing role and match status-related demands to design specific training plans.


Resumo Atualmente, a quantificação da carga durante o treino e competição em todos os desportos é importante para a prevenção de lesões, sessões de treino específicas e melhoria do desempenho dos jogadores. Os objetivos do presente estudo foram descrever o perfil de carga externa dos jogadores de handebol a nível amador e comparar a posição de jogo e as diferenças relacionadas com os resultados de um jogo oficial da 2ª Divisão Regional masculino. Foram analisados 19 jogadores de handebol por meio do WIMU PROTM electronic performance and tracking systems (EPTS) com tecnologia de localização em interiores ultrawide-band (UWB). A análise estatística foi composta por um teste T para amostra independente e ANOVA unidirecional com posthoc de Bonferroni. No handebol amador, as maiores exigências são compostas por deslocamentos de intensidade aeróbica (<12 km/h, 76% de tempo de jogo) e impactos de baixa intensidade (<5G). Foram encontradas diferenças entre as posições de jogo em que os alas obtiveram os maiores valores em ações de alta intensidade, centros no volume de exigência e jogadores defensivos especializados em impactos. Além disso, as equipes vencedoras realizaram maiores exigências de alta intensidade, tanto em deslocamentos como em mudanças de velocidade. Esses resultados fazem a primeira aproximação às exigências do handebol amador, considerando as exigências relacionadas com o papel de jogo e status de jogo para desenhar planos de treino específicos.

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